Research and Publications

Lumbar decompression surgery for cauda equina syndrome: A meta-analysis and systematic review of the safety of operating out of hours,

The Surgeon Sept 2025

Henry A. Crouch-Smith, Iain Feeley, Margaret K. Lee, Nicholas Carleton-Bland, Simon Clark, Matthew Wilby.

Characterizing the Management of Inpatients With Ossified Posterior Longitudinal Ligament (OPLL): A 10-year Tertiary Center UK Study.

Clinical Spine Surgery Sept 2025

Inam, Masna; Roylance, Anthony; Bakhsh, Ali MRCS; Lee, Maggie; Clark, Simon PhD; Wilby, Martin J. PhD.

Causes and consequences of 'delays' in the diagnosis of spinal dural arterio-venous fistula; An illustrative case series, review and commentary

Journal of Clinical Neuroscience Aug 2025

Derek Yull; Dani Chene; Simon Clark; Josh Yee; Yun-Hom Yau; Ian Whittle

A qualitative study of experiencing cauda equina syndrome and its aftercare in the UK.

Spinal Cord August 2025

Nisaharan Srikandarajah, Simon Clark, Martin Wilby, Tony Marson, and Adam Noble

Patient-Reported Outcomes In Primary Spinal Intradural Tumours: A Systematic Review

Spinal Cord March 2024

Mr Ahmad M. S. Ali, Mr Mohammad A. Mustafa, Dr Omar M. E. Ali, Dr Conor S. Gillespie, Dr George M. Richardson, Mr Simon Clark, Mr Martin J. Wilby, Mr Christopher P. Millward, Mr Nisaharan Srikandarajah

Identification and Assessment of Outcome Measurement Instruments in Cauda Equina Syndrome: A systematic Review

Global Spine Journal January 2024

George Richardson, Christopher Milward, James Mitchell, Simon Clark, Martin Wilby, Tony Marson, Paula Williamson, Nisaharan Srikandarajah

Lumbar Decompression Surgery For Cauda Equina Syndrome Compared To Non-Cauda Equina Syndrome: An Analysis Of Complications And Outcomes

The Surgeon Sept 2025

Henry A. Crouch-Smith, George M. Richardson, Nisaharan Srikandarajah, Simon Clark, Martin J. Wilby

A systematic review and meta-analysis of vertebral artery injury after cervical spine trauma

Global Spine Journal November 2023

Kartik Goyal, Jesvin Sunny, Conor Gillespie , Martin Wilby, Simon Clark, Radek Kaiser , Michael Fehlings, Nisaharan Srikandarajah

Definition and surgical timing in cauda equina syndrome- An updated systematic review

PLOS one May 2023

Mustafa MA, Richardson GE, Gillespie CS, Islim AI, Wilby M, Clark S, Srikandarajah N

Anterior to Psoas lumbar and lumbosacral combined with posterior reconstruction in Adult Spinal Deformity:A bicentric European study

Brain and Spine May 2023

Marco Teli, Giuseppe E Umana, Paulo Palmisciano, Maggie K Lee, Simon R Clark, Christian Soda

Cerebrospinal fluid hydrothorax in a rehabilitation medicine patient following thoracotomy for thoracic disc protrusion

Adv Clin Neurosci Rehabil 2022

Boardman A, Manuel A, Shaw R, Lari S, Clark S.

Presentation, management and outcomes of cauda equina syndrome upto one year after surgery using clinician and participant reporting: A multicentre prospective cohort study

Lancet Reg health Eur Nov 2022

UCES collaborators

Anterolateral thoracic approach for thoracic discectomy using pedicle marking and O-arm

British Journal of Neurosurgery Nov 2021

Aljeirou Alcachupas, Nisaharan Srikandarajah, Nicholas Carleton-Bland, Simon Clark

Management of malignant spinal cord compression

Surgery July 2021

Surya Gandham, Simon Clark, Marcus DeMatas

Surgical microdiscectomy versus transforaminal epidural steroid injection in patients with sciatica secondary to herniated lumbar disc (NERVES): a phase 3 multicentre, open-label, randomised controlled trial and economic evaluation

Lancet rheumatology May 2021

Martin John Wilby, Ashley Best, Eifiona Wood, Girvan Burnside, Emma Bedson, Hannah Short, Dianne Wheatley, Daniel Hill-McManus, Manohar Sharma, Simon Clark, Ganesan Baranidharan, Cathy Price, Richard Mannion, Prof Peter J Hutchinson, Prof Dyfrig A Hughes, Prof Anthony Marson, Prof Paula R Williamson

Primary lumbar decompression using ultrasonic bone curette compared to conventional technique

British Journal of Neurosurgery 2020

Richard DC Moon, Nisarahan Srikandarajah, Simon Clark, Martin J Wilby

Cauda Equina Syndrome Core Outcome Set (CESCOS): An international patient and healthcare professional consensus for research studies.

PLoS ONE 15(1)2020

Srikandarajah N, Noble A, Clark S, Wilby M, Freeman BJC, Fehlings MG, et al

Protocol for the development of a core outcome set for cauda equina syndrome: systematic literature review, qualitative interviews, delphi survey and consensus meeting

BMJ OPEN 2019

Srikandarajah N, Noble A, Wilby M, Clark S, Williamson P, Marson T

Outcomes reported after surgery for cauda equina syndrome: a systematic literature review

Spine 2018

Srikandarajah N, Noble A, Wilby M, Clark S, Williamson P, Marson T

Nerve root block versus surgery (NERVES) for the treatment of radicular pain secondary to a prolapsed intervertebral disc herniation: study protocol for a multi-centre randomised controlled trial

Trials 2018

Martin John Wilby; Carolyn Hopkins; Emma Bedson; Sue Howlin; Girvan Burnside; Elizabeth J Conroy; Dyfrig Hughes; Manohar Sharma; Anthony Marson; Simon Clark; Paula Williamson

Patient reported outcomes in lumbar decompression for degenerative spondylolisthesis. A tangible benefit?

The spine journal 2017 17(3)S25

Elliot M, Srikandarajah N, Clark S, Wilby M

Systematic literature review of outcomes after surgery for cauda equina syndrome

the spine journal 2017 17(3)S26-7

Srikandarajah N,Noble A, Clark S, Wilby M, Williamson P, Marson T

Does surgical intervention within 48 hours in Cauda Equina Syndrome improve bladder outcome?

Spine 2015 40(8)

Srikandarajah N, Boissard-Cooke MA, Clark S, Wilby MJ

Cervical vertebral fusion with anterior meningocele

Neuroradiology J 2015 28(2)

Matthew J Gallagher, Emmanuel Chavredakis, David Carter, Manesh Bhojak, Michael D Jenkinson, Simon R Clark

Long-term survival analysis of atypical meningiomas: survival rates, prognostic factors, operative and radiotherapy treatment.

Acta neurochirurgica 2014

Hammouche S, Clark S, Wong AH, Eldridge P, Farah JO.

Conservative management of type II and III odontoid fractures in the elderly at a regional spine centre: A prospective and retrospective cohort study

Br J Neurosurgery 2014

Amit Patel , Rasheed Zakaria , Rafi d Al-Mahfoudh , Simon Clark , Chris Barrett , Zaid Sarsam , Robin Pillay , Tim Drummond Pigott & Martin J. Wilby

Spinal Dural Arteriovenous Fistulas - presentation, management and outcome in a single neurosurgical institution

Br J Neurosurgery Dec 2012

S.Clark, G. Powell, J. Kandasamy, M. Lee, H. Nahser, T. Pigott

Inflammation as a predictor for delayed cerebral ischaemia after subarachnoid haemorrhage

J Neurointervent Surg Sept 2012 10(1136)

Catherine J McMahon, Stephen Hopkins, Andy Vail, Andrew King, Debi Smith, Karen Illingworth, Simon Clark, Nancy J Rothwell, Pippa J Tyrrell

Radiological assessment of spinal fusion

Journal of the American Academy of Orthopaedic Surgeons Nov 2012 20(11)

Selby MD/Clark SR, Hall DJ, Freeman BJC

Electromagnetic (EM) Stereotactic Ventriculo-Peritoneal CSF shunting for Idiopathic Intracranial Hypertension: a successful step forward? - A Technical Report

World Neurosurgery Jan 2011 75(1)

Kandasamy J, Hayhurst C, Clark S, Jenkinson M, Byrne P, Karabatsou K, Mallucci C

Cognitive and functional outcome in spina bifida-Chiari II malformation

Childs Nerv Syst. 2011 Jun;27(6)

Jenkinson MD, Campbell S, Hayhurst C, Clark S, Kandasamy J, Lee MK, Flynn A, Murphy P, Mallucci CL

Effect of electromagnetic-navigated shunt placement on failure rates:a prospective multicentre study

Journal of Neurosurgery Dec 2010 113(6)

Hayhurst C, Beems T, Jenkinson MD, Byrne P, Clark S, Kandasamy J, Goodden J, Tewarie RD, Mallucci C

The role of endoscopic third ventriculostomy in adult patients with hydrocephalus

Journal of Neurosurgery May 2009 110(5)

Jenkinson MD, Hayhurst C, Kandasamy J, Al-Jumaily M, Clark S, Mallucci C.

Electromagnetic guided neuroendoscopy in the paediatric population.

Journal of Neurosurgery (paediatrics) April 2009 3(4)

Sangra M, Clark S, Hayhurst C, Mallucci C

Alkaptonuria presenting with onchronotic spondyloarthropathy

British Journal of Neurosurgery Dec 2008 22(6)

Al-Mahfoudh R, Clark S, Buxton N

A neurosurgical golf injury

Clinical Medicine:case reports 2008

Al-Mahfoudh R, Clark S, Kandasamy J, May P

The use of non invasive electromagnetic neuronavigation in the management of paediatric slit ventricle syndrome and complex hydrocephalus

Journal of Neurosurgery (paediatrics) Dec 2008 2(6)

Clark S, Sangra M, Hayhurst C, Jenkinson M, Kandasamy J, Mallucci C

Interleukin-1 receptor antagonist penetrates human brain at experimentally therapeutic concentrations

Journal of Cerebral Blood Flow and Metabolism 2008 28(2) 387-94

Simon R Clark, Catherine J.McMahon, Iva Gueorguieva, Malcolm Rowland, Sylvia Scarth, Pippa J. Tyrell, Stephen J. Hopkins, Nancy J. Rothwell

Pharmacokinetic modelling of interleukin-1 receptor antagonist in subarachnoid haemorrhage

British Journal of Clinical Pharmacology Jan 2008 65(3) 317-25

Iva Gueorguieva , Simon R Clark, Catherine J. McMahon , Sylvia Scarth, Pippa J. Tyrell, Stephen J. Hopkins, Nancy J. Rothwell, Malcolm Rowland

Peripheral administration of interleukin-1 receptor antagonist (IL-1ra) reduces ischaemic brain damage in the rat

Journal of Cerebral Blood Flow and Metabolism 2005 25(S45)

Clark S, Allan S, Rothwell N

University of Manchester

The Impact Of Basal Skull Fractures On Outcome Following Head Injury

Acta Neurochirurgica 2002 144(7) Supplementum

Clark S, Ogungbo A, Mendelow AD

Newcastle General Hospital